Analytical chemistry Assignment Example | Topics and Well Written Essays - 750 words

Analytical chemistry - Assignment Example n used in the advancement of a sensitive method that can be used to judge ABZ put in pharmaceutical formulations through the use of differential pulse voltammetry (DPV) method (Lourencao, Baccarin, Medeiros, Rocha-Filho & Fatibello-Filho, 2013). The main aim was to provide the above information on the above issue both in veterinary and human medicine. The paper adds to the few studies that have been done on electrochemical behavior and the quantification of ABZ. It also serves to add information on the use of several methods that have been used in the definition of ABZ and its main metabolites including chromatographic and spectrophotometric methods. The electrochemical behavior of the ABZ was studied using three voltammetric techniques that included cyclic voltammetry (CV), square-wave voltammetry (SWV) and differential pulse voltammetry (DPV) methods. All the three methods were used to determine which one among them was the best in the evaluations to enable the authors come up with a trustworthy result and conclusion on the investigations. The cyclic voltammetry was used was only used for preliminary studies because it is not as sensitive and detailed as the other procedures (Lourencao, Baccarin, Medeiros, Rocha-Filho & Fatibello-Filho, 2013). The three methods were used to find the best conditions for determining ABZ. After optimization of the of the limitations of the experiment for the methods, the result was used to draw curves by adding the aliquots of the stock solution of the ABZ to electrochemical cell that had 10 mL of 0.05 mol L-1 H2SO4. All the experiments were done through an Autolab PGSTAT-30 potentiostat that was controlled by the GPES 4.9 software. The experiment also employed the use of a three-electrode sell system where a BDD electrode was the working one, an Ag electrode as the reference and the platinum wire as the auxiliary electrode. The experiment also used an LC-10 AT Shimadzu system to determine the ABZ through a high performance